Cato Brede | University of Stavanger

Faculty of Science and Technology
Department of Chemistry, Bioscience and Environmental Engineering

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Bio

Responsible for development, validation and quality assurance of LC-MS / MS methods for clinical analysis at Department of Medical Biochemistry, Stavanger University Hospital (SUS). Associate professor at Department of Chemistry, Bioscience, and Environmental Engineering, University of Stavanger. Tutor of Instrumental Analysis course (MLJ 540). Recent activity has been the implementation of LC-MS/MS for quantitative analysis at UiS, and participation in a small startup company (FishLab AS).

Research areas include new methods and tools for the quantification of proteins, metabolites, hormones, lipids and drugs, in human samples, for assessment as potential biomarkers for various conditions, such as diabetes and autoimmune disease.

Publications

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Vitenskapelige publikasjoner
- Urge, Alemnesh Yirda; Pampanin, Daniela Maria; Martino, Maria Elena; Knudsen, David Lausten; Brede, Cato
  
  (2023)
  Salting-Out Assisted Liquid-Liquid Extraction for UPLC-MS/MS Determination of Thyroxine and Steroid Hormones in Human Serum and Fish Plasma.
  Separations.
  
  ISSN 2297-8739.
  
  Volum 10.
  
  Hefte 4.
  
  s.1-17.
  
  DOI: 10.3390/separations10040240
- Oppen, Kjersti; Brede, Cato; Skadberg, Øyvind; Steinsvik, Trude; Holter, Jan Cato; Michelsen, Annika Elisabet; Heggelund, Lars
  
  (2023)
  Hepcidin analysis in pneumonia: Comparison of immunoassay and LC-MS/MS.
  Annals of Clinical Biochemistry.
  
  ISSN 0004-5632.
  
  Volum 60.
  
  Hefte 5.
  
  s.298-305.
  
  DOI: 10.1177/00045632231159529
- Meling, Vanessa Andrea; Berge, Kjetil; Knudsen, David Lausten; Rønning, Per Ola; Brede, Cato
  
  (2022)
  Monitoring Farmed Fish Welfare by Measurement of Cortisol as a Stress Marker in Fish Feces by Liquid Chromatography Coupled with Tandem Mass Spectrometry.
  Molecules.
  
  ISSN 1431-5157.
  
  Volum 27.
  
  Hefte 8.
  
  s.1-12.
  
  DOI: 10.3390/molecules27082481
- Oppen, Kjersti; Ueland, Thor; Michelsen, Annika Elisabet; Aukrust, Pål; Steinsvik, Trude; Skadberg, Øyvind; Brede, Cato; Siljan, William Ward; Husebye, Einar; Holter, Jan Cato; Heggelund, Lars
  
  (2022)
  Hepcidin predicts 5-year mortality after community-acquired pneumonia.
  Infectious Diseases.
  
  ISSN 2374-4235.
  
  Volum 54.
  
  Hefte 6.
  
  s.403-409.
  
  DOI: 10.1080/23744235.2021.2022194
- Kvivik, Ingeborg; Jonsson, Grete; Omdal, Roald; Brede, Cato
  
  (2021)
  Sample Preparation Strategies for Antibody-Free Quantitative Analysis of High Mobility Group Box 1 Protein.
  Pharmaceuticals.
  
  ISSN 1424-8247.
  
  Volum 14.
  
  Hefte 6.
  
  DOI: 10.3390/ph14060537
- Oppen, Kjersti; Ueland, Thor; Siljan, William Ward; Skadberg, Øyvind; Brede, Cato; Lauritzen, Trine; Aukrust, Pål; Steinsvik, Trude; Husebye, Einar; Michelsen, Annika; Holter, Jan Cato; Heggelund, Lars
  
  (2021)
  Hepcidin and ferritin predict microbial etiology in community-acquired pneumonia.
  Open Forum Infectious Diseases.
  
  ISSN 2328-8957.
  
  Volum 8.
  
  Hefte 4.
  
  DOI: 10.1093/ofid/ofab082
- Kafle, Bijay; Baak, Jan P.A.; Brede, Cato
  
  (2021)
  Major bioactive chemical compounds in Astragali Radix samples from different vendors vary greatly.
  PLOS ONE.
  
  ISSN 1932-6203.
  
  Volum 16.
  
  Hefte 7.
  
  s.1-13.
  
  DOI: 10.1371/journal.pone.0254273
- Slimestad, Rune; Fossen, Torgils; Brede, Cato
  
  (2020)
  Flavonoids and other phenolics in herbs commonly used in Norwegian commercial kitchens.
  Food Chemistry.
  
  ISSN 0308-8146.
  
  Volum 309:125679.
  
  s.1-8.
  
  DOI: 10.1016/j.foodchem.2019.125678
- Kafle, Bijay; Baak, Jan P.A.; Brede, Cato
  
  (2020)
  Quantification by LC–MS/MS of astragaloside IV and isoflavones in Astragali radix can be more accurate by using standard addition.
  Phytochemical Analysis.
  
  ISSN 0958-0344.
  
  s.1-8.
  
  DOI: 10.1002/pca.2994
- Kvamsøe, Marianne Meling; Hansen, Kristina Ravnås; Skadberg, Øyvind; Vethe, Nils Tore; Brede, Cato
  
  (2020)
  Salting Out-Assisted Liquid–Liquid Extraction for Liquid Chromatography–Tandem Mass Spectrometry Measurement of Tacrolimus, Sirolimus, Everolimus, and Cyclosporine a in Whole Blood.
  Therapeutic Drug Monitoring.
  
  ISSN 0163-4356.
  
  Volum 42.
  
  Hefte 5.
  
  s.695-701.
  
  DOI: 10.1097/FTD.0000000000000794
- Thorsen, Inga Strand; Bleskestad, Inger Hjørdis; Åsberg, Anders; Hartmann, Anders; Skadberg, Øyvind; Brede, Cato; Ueland, Thor; Pasch, Andreas; Reisæter, Anna Varberg; Gøransson, Lasse
  
  (2019)
  Vitamin D as a risk factor for patient survival after kidney transplantation: A prospective observational cohort study.
  Clinical Transplantation.
  
  ISSN 0902-0063.
  
  Volum 33:e13517.
  
  Hefte 5.
  
  s.1-12.
  
  DOI: 10.1111/ctr.13517
- Bårdsen, Kjetil; Brede, Cato; Kvivik, Ingeborg; Kvaløy, Jan Terje; Jonsdottir, Kristin; Tjensvoll, Anne Bolette; Ruoff, Peter; Omdal, Roald
  
  (2019)
  Interleukin-1-related activity and hypocretin-1 in cerebrospinal fluid contribute to fatigue in primary Sjögren's syndrome.
  Journal of Neuroinflammation.
  
  ISSN 1742-2094.
  
  Volum 16.
  
  s.1-9.
  
  DOI: 10.1186/s12974-019-1502-8
- Bårdsen, Kjetil; Gjerstad, Michaela D; Partinen, Markku; Kvivik, Ingeborg; Tjensvoll, Anne Bolette; Ruoff, Peter; Omdal, Roald; Brede, Cato
  
  (2019)
  Considerably Lower Levels of Hypocretin-1 in Cerebrospinal Fluid Is Revealed by a Novel Mass Spectrometry Method Compared with Standard Radioimmunoassay.
  Analytical Chemistry.
  
  ISSN 0003-2700.
  
  Volum 91.
  
  Hefte 14.
  
  s.9323-9329.
  
  DOI: 10.1021/acs.analchem.9b02710
- Larssen, Eivind; Brede, Cato; Hjelle, Anne; Tjensvoll, Anne Bolette; Norheim, Katrine Brække; Bårdsen, Kjetil; Jonsdottir, Kristin; Ruoff, Peter; Omdal, Roald; Nilsen, Mari Mæland
  
  (2019)
  Fatigue in primary Sjögren's syndrome: A proteomic pilot study of cerebrospinal fluid.
  SAGE Open Medicine.
  
  ISSN 2050-3121.
  
  Volum 7.
  
  s.1-10.
  
  DOI: 10.1177/2050312119850390
- Slimestad, Rune; Fossen, Torgils; Brede, Cato
  
  (2019)
  Flavonoids and other phenolics in herbs commonly used in Norwegian commercial kitchens.
  Food Chemistry.
  
  ISSN 0308-8146.
  
  DOI: 10.1016/j.foodchem.2019.125678
- Hirtz, Christophe; Bros, Pauline; Brede, Cato; Lescuyer, Pierre; Maceski, Aleksandra M.; Vialaret, Jérôme; Delatour, Vincent; Lehmann, Sylvain
  
  (2018)
  Regulatory context and validation of assays for clinical mass spectrometry proteomics (cMSP) methods.
  Critical reviews in clinical laboratory sciences.
  
  ISSN 1040-8363.
  
  Volum 55.
  
  Hefte 5.
  
  s.346-358.
  
  DOI: 10.1080/10408363.2018.1470159
- Lehmann, Sylvain; Brede, Cato; Lescuyer, Pierre; Cocho, José A.; Vialaret, Jérôme; Bros, Pauline; Delatour, Vincent; Hirtz, Christophe
  
  (2017)
  Clinical mass spectrometry proteomics (cMSP) for medical laboratory: What does the future hold?.
  Clinica Chimica Acta.
  
  ISSN 0009-8981.
  
  Volum 467.
  
  s.51-58.
  
  DOI: 10.1016/j.cca.2016.06.001
- Nadarajah, Nirosa; Skadberg, Øyvind; Adaway, Joanne; Brede, Cato
  
  (2017)
  Multiplexed analysis of steroid hormones in saliva by LC-MS/MS With 2-hydrazinopyridine derivatization..
  Clinical Mass Spectrometry.
  
  ISSN 2376-9998.
  
  Volum 4-5.
  
  Hefte April.
  
  DOI: 10.1016/j.clinms.2017.08.001
- Brede, Cato; Hop, Beate; Jørgensen, Kåre Bredeli; Skadberg, Øyvind
  
  (2016)
  Measurement of glycated albumin in serum and plasma by LC-MS/MS.
  Scandinavian Journal of Clinical and Laboratory Investigation.
  
  ISSN 0036-5513.
  
  Volum 76.
  
  Hefte 3.
  
  s.195-201.
  
  DOI: 10.3109/00365513.2015.1129671
- Larssen, Eivind; Brede, Cato; Hjelle, Anne; Øysæd, Kjell Birger; Tjensvoll, Anne Bolette; Omdal, Roald; Ruoff, Peter
  
  (2015)
  A rapid method for preparation of the cerebrospinal fluid proteome.
  PROTEOMICS - Clinical Applications.
  
  ISSN 1862-8346.
  
  Volum 15.
  
  Hefte 1.
  
  s.10-15.
  
  DOI: 10.1002/pmic.201400096
- Bräunlich, Paula Marie; Slimestad, Rune; Wangensteen, Helle; Brede, Cato; Malterud, Karl Egil; Barsett, Hilde
  
  (2013)
  Extracts, Anthocyanins and Procyanidins from Aronia melanocarpa eas Radical Scavengers and Enzyme Inhibitors.
  Nutrients.
  
  ISSN 2072-6643.
  
  Volum 5.
  
  Hefte 3.
  
  s.663-678.
  
  DOI: 10.3390/nu5030663
- Lehmann, Sylvain; Hoofnagle, Andrew; Hochstrasser, Denis; Brede, Cato; Glueckmann, Matthias; Cocho, José A.; Ceglarek, Uta; Lenz, Christof; Vialaret, Jérôme; Scherl, Alexander; Hirtz, Christophe
  
  (2013)
  Quantitative Clinical Chemistry Proteomics (qCCP) using mass spectrometry: general characteristics and application.
  Clinical Chemistry and Laboratory Medicine.
  
  ISSN 1434-6621.
  
  Volum 51.
  
  Hefte 5.
  
  s.919-935.
  
  DOI: 10.1515/cclm-2012-0723
- Björkblom, Benny; Adilbayeva, Altynai; Maple-Grødem, Jodi; Piston, Dominik; Ökvist, Mats; Xu, Xiang Ming; Brede, Cato; Larsen, Jan Petter; Møller, Simon Geir
  
  (2013)
  Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity.
  Journal of Biological Chemistry.
  
  ISSN 0021-9258.
  
  Volum 288.
  
  Hefte 31.
  
  s.22809-22820.
  
  DOI: 10.1074/jbc.M113.482091
- Næsgaard, Patrycja; Leon de la Fuente, Ricardo; Nilsen, Stein Tore; Woie, Leik; Årsland, Torbjørn; Brede, Cato; Staines, Harry; Nilsen, Dennis W.T.
  
  (2012)
  Serum 25(OH)D is a 2-year predictor of all-cause mortality, cardiac death and sudden cardiac death in chest pain patients from Northern Argentina.
  PLOS ONE.
  
  ISSN 1932-6203.
  
  Volum 7.
  
  Hefte 9:e43228.
  
  DOI: 10.1371/journal.pone.0043228
- Hanasand, Marita; Omdal, Roald; Norheim, Katrine Brække; Gøransson, Lasse G; Brede, Cato; Jonsson, Grete
  
  (2012)
  Improved detection of advanced oxidation protein products in plasma.
  Clinica Chimica Acta.
  
  ISSN 0009-8981.
  
  Volum 413.
  
  Hefte 9-10.
  
  s.901-906.
  
  DOI: 10.1016/j.cca.2012.01.038
- Uleberg, Kai-Erik; Munk, Ane Cecilie Dæhli; Brede, Cato; Gudlaugsson, Einar; Van Diermen, Bianca; Skaland, Ivar; Malpica, Anais; Janssen, Emilius Adrianus Maria; Hjelle, Anne; Baak, Jan P.A.
  
  (2011)
  Discrimination of grade 2 and 3 cervical intraepithelial neoplasia by means of analysis of water soluble proteins recovered from cervical biopsies.
  Proteome Science.
  
  ISSN 1477-5956.
  
  Volum 9.
  
  DOI: 10.1186/1477-5956-9-36
- Olsen, Kristine Marie; Slimestad, Rune; Lea, Unni Synnøve; Brede, Cato; Løvdal, Trond Karsten; Ruoff, Peter; Verheul, Michel; Lillo, Cathrine
  
  (2009)
  Temperature and nitrogen effects on regulators and products of the flavonoid pathway: experimental and kinetic model studies.
  Plant, Cell and Environment.
  
  ISSN 0140-7791.
  
  Volum 32.
  
  Hefte 3.
  
  s.286-299.
  
  DOI: 10.1111/j.1365-3040.2008.01920.x
- Slimestad, Rune; Vangdal, Eivind; Brede, Cato
  
  (2009)
  Analysis of Phenolic Compounds in Six Norwegian Plum Cultivars (Prunus domestica L.).
  Journal of Agricultural and Food Chemistry.
  
  ISSN 0021-8561.
  
  Volum 57.
  
  Hefte 23.
  
  s.11370-11375.
  
  DOI: 10.1021/jf902054x
Bøker og kapitler
Formidling
- Brede, Cato; Vethe, Nils T.; Skadberg, Øyvind
  
  (2021)
  The Question of Accuracy Versus Interlaboratory Agreement for Monitoring the Immunosuppressants Everolimus and Sirolimus.
  Therapeutic Drug Monitoring.
  
  ISSN 0163-4356.
  
  Volum 43.
  
  Hefte 3.
  
  s.444-446.
  
  DOI: 10.1097/FTD.0000000000000892
- Næsgaard, Patrycja; Pønitz, Volker; Leon de la Fuente, Ricardo; Andersen, Trygve Brugger; Nilsen, Stein Tore; Grundt, Heidi; Brede, Cato; Staines, Harry; Nilsen, Dennis W.T.
  
  (2016)
  
  The Prognostic Utility of Vitamin D Across Continents in Patients with Suspected Acute Coronary Syndrome. Circulation. 2016; 133: AP028.
  
  EPI Lifestyle Scientific Sessions - American Heart Association;
  
  2016-03-01 - 2016-03-04.
- Naesgaard, Patrycja; Grundt, Heidi; Brede, Cato; Nilsen, Dennis W.T.
  
  (2014)
  
  The Effect on Vitamin D Levels of Long-term High-dose Treatment With a Concentrated Omega-3 Compound (Omacor®/Lovaza®) in Patients Hospitalized With a Myocardial Infarction. Core 2. Epidemiology and Prevention of CV Disease: Physiology, Pharmacology and LifestyleSession Title: Nutrition in CVD Risk and Prevention I. Circulation. 2014; 130: A17245.
  
  American Heart Association's 2014 Scientific Sessions and Resuscitation Science Symposium;
  
  2014-11-15 - 2014-11-19.
- Braünlich, Marie; Slimestad, Rune; Wangensteen, Helle; Brede, Cato; Malterud, Karl Egil; Barsett, Hilde
  
  (2012)
  
  Extracts, anthocyanins and procyanidins from Aronia melanocarpa as radical scavengers and enzyme inhibitors.
  
  International Congress on Natural Product Research;
  
  2012-07-28 - 2012-08-01.
- Naesgaard, Patrycja; León de la fuente, Ricardo; Nilsen, Stein Tore; Aarsland, Torbjørn; Woie, Leik; Grundt, Heidi; Brede, Cato; Staines, Harry; Gallo, Patricio; Dib Ashur, Silvia A.; Torino, Augusto Fernando Mautner; Nilsen, Dennis W.T.
  
  (2012)
  
  Circulation 2012;125(10)Suppl:AP310. The Distribution of Total- and HDL Cholesterol and Triglycerides is Significantly Different across Quartiles of Vitamin D in Chest-Pain Patients with a Suspected Acute Coronary Syndrome.
  
  AHA council, EPI/NPAM2012 Scientific Sessions, March 13-16, 2012, San Diego, California..;
  
  2012-03-13 - 2012-03-16.
- Naesgaard, Patrycja; Pønitz, Volker; Andersen, Trygve Brugger; Aarsetøy, Hildegunn; Grundt, Heidi; Brede, Cato; Staines, Harry; Nilsen, Dennis W.T.
  
  (2012)
  
  Circulation 2012;125(10)Suppl:AP325. The Prognostic Utility of Vitamin D and Its Seasonal Variation in Chest Pain Patients with Suspected Acute Coronary Syndrome Recruited from a Coastal Population in Western-Norway.
  
  AHA council, EPI/NPAM2012 Scientific Sessions, March 13-16, 2012, San Diego, California..;
  
  2012-03-13 - 2012-03-16.
- Bräunlich, M.; Slimestad, Rune; Wangensteen, Helle; Brede, Cato; Malterud, Karl Egil; Barsett, Hilde
  
  (2012)
  
  Extracts, anthocyanins and procyanidins from Aronia melanocarpa as radical scavengers and enzyme inhibitors.
  
  Planta Medica.
  
  ISSN 0032-0943.
  
  Volum 78.
  
  Hefte 11.
  
  s.1120-1121.
- Naesgaard, Patrycja; León de la fuente, Ricardo; Gallo, Patricio; Brede, Cato; Grundt, Heidi; Aarsland, Torbjørn; Woie, Leik; Nilsen, Stein Tore; Staines, Harry; Nilsen, Dennis W.T.
  
  (2011)
  
  Vitamin D Status is a 2-Year Predictor of All-Cause Mortality and Cardiac Death in Chest Pain Patients: A Prognostic Study from Salta, Northern-Argentina. Circulation 2011; 124(21): Supplement. Abstract 10377.
  
  American Heart Association Scientific Sessions 2011;
  
  2011-11-12 - 2011-11-16.
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